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hrp0097rfc7.1 | Sex differentiation, gonads and gynaecology or sex endocrinology | ESPE2023

Penile width increases more clearly than penile length during minipuberty: a longitudinal study of 136 healthy infant boys

Mola Gylli , Siegfried Busch Alexander , Lindhardt Ljubicic Marie , N. Upners Emmie , Bistrup Fischer Margit , Juul Anders , P. Hagen Casper

Background: In minipuberty, the male hypothalamic-pituitary-gonadal (HPG) axis is transiently activated triggering a surge in reproductive hormones causing growth of the genitalia. Longitudinal individual growth of the infant penis during minipuberty and associations to the HPG axis and IGF-I have not been thoroughly assessed.Aim: To describe the development of penile length and width as well as their relation to serum c...

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hrp0097rfc7.6 | Sex differentiation, gonads and gynaecology or sex endocrinology | ESPE2023

Prenatal AnoGenital Distance (AGD) by ultrasonography in 571 fetuses and correlation to postnatal AGD: A longitudinal cohort study of healthy males and females

Bistrup Fischer Margit , Mola Gylli , Scheel Lone , Kristine Hegaard Hanne , Sundberg Karin , Juul Anders , P Hagen Casper

Background: The anogenital distance (AGD) is a well-known measure in rodents used to distinguish male and female pubs. Likewise, AGD display sex-specific differences in humans. It is considered a postnatal readout of early androgen exposure in fetal life. Thus, in postnatal life AGD is longer in boys than in girls, reduced in infants born with cryptorchidism and hypospadias as well as in boys exposed to anti-androgenic agents in fetal life. However, little is ...

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ESPE Abstracts

Penile width increases more clearly than penile length during minipuberty: a longitudinal study of 136 healthy infant boys

Prenatal AnoGenital Distance (AGD) by ultrasonography in 571 fetuses and correlation to postnatal AGD: A longitudinal cohort study of healthy males and females

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